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  • WZ4003

    2025-08-14

    WZ4003

    Author: ApexBio

    spu:

    B1374

    CAS:

    1214265-58-3

    purity:

    0.9932

    shortsummary:

    NUAK1/2 inhibitor, potent and selective

    Dibutyryl-cAMP APExBIO

    Formula:

    C25H29ClN6O3

    M.Wt:

    496.99

    Chemical Name:

    N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide

    SMILES:

    CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC

    Solubility:

    insoluble in H2O; ≥2.68 mg/mL in EtOH with gentle warming and ultrasonic; ≥7.85 mg/mL in DMSO with gentle warming

    Storage:

    Store at -20°C

    Physical Appearance:

    A solid

    DeliveryTime:

    In stock

    199596-05-9 In stock

    ShippingType:

    Blue ice

    description:

    WZ4003 is a potent and selective inhibitor of NUAK1 and NUAK2 with IC50 values of 20 and 100 nM, respectively [1].

    WZ4003 PMC11133856

    related websites:

    APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 3117 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.

    https://www.apexbt.com/